E2F Transcription Factor 6 (E2F6) (Middle Region) 抗體

抗原
E2F Transcription Factor 6 (E2F6)
別名 E2F-6, AI462434, E2F6b, EMA
抗原表位
其他選擇 Middle Region
Internal Region(8),AA 1-281 (5),C-Term (4),Middle Region (3),AA 1-282 (2),AA 1-251 (1),AA 141-190 (1),AA 59-281 (1),Glu170 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Human
Human(59),Rat ((Rattus)) (34),Murine (31),Bovine (2),Dog (Canine) (2)
宿主
其他選擇 Rabbit
Rabbit(45),Mouse (11),Goat (4)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(46),ELISA (20),Immunohistochemistry (IHC) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Immunocytochemistry (ICC) (4),Immunofluorescence (IF) (4),Enzyme Immunoassay (EIA) (3),Immunoassay (IA) (3),Immunoprecipitation (IP) (3),Dot Blot (DB) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2)
[Pubmed] 2 references available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

E2F Transcription Factor 6 (E2F6) (Middle Region) 抗體

產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the middle region of human E2F6
序列 HEQIVIAVKA PAETRLDVPA PREDSITVHI RSTNGPIDVY LCEVEQGQTS
預(yù)測(cè)反應(yīng) Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Bovine : 90 %, Guinea pig : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against E2F6. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Protein A purified

目標(biāo)詳細(xì)情況

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E2F Transcription Factor 6 (E2F6) (Middle Region) 抗體目標(biāo)詳細(xì)情況

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別名 E2F6
背景 E2F6 is a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants encoding several different isoforms have been found for this gene.
分子量 14 kDa
基因ID 1876
NCBI Accession NP_997705, NM_212540
UniProt Q6Q9Z5
研究領(lǐng)域 Chromatin and Nuclear Signaling, Transcription Factors

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E2F Transcription Factor 6 (E2F6) (Middle Region) 抗體使用細(xì)節(jié)

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說(shuō)明

Antigen size: 129 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 100 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C

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