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Autophagy/beclin-1 Regulator 1 (AMBRA1) (C-Term) 抗體
抗原
Autophagy/beclin-1 Regulator 1 (AMBRA1)
別名 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, mKIAA1736, Nyw1, DCAF3, WDR94
抗原表位
其他選擇 C-Term
N-Term(23),C-Term (13),AA 1-50 (2),AA 27-55 (2),AA 1200-1250 (1),AA 14-239 (1),AA 807-1092 (1),Internal Region (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(59),Murine (47),Rat ((Rattus)) (30),Chicken (13),Dog (Canine) (12),Bovine (1)
宿主
其他選擇 Rabbit
Rabbit(66),Mouse (1)
克隆類型
多克隆
標記
其他選擇 非結合性
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),FITC (1),HRP (1)
應用范圍
其他選擇 ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
Western Blotting (WB)(56),Immunohistochemistry (IHC) (29),ELISA (27),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (7),Enzyme Immunoassay (EIA) (4),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (4),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunoassay (IA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 24至29個工作日
Autophagy/beclin-1 Regulator 1 (AMBRA1) (C-Term) 抗體
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免疫原 The immunogen for anti-Ambra1 antibody: antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human Ambra1.
預測反應 Human Mouse Rat
產品特性 Autophagy, The Process Of Bulk Degradation Of Cellular Proteins Through An Autophagosomic-Lysosomal Pathway Is Important For Normal Growth Control And May Be Defective In Tumor Cells. It Is Involved In The Preservation Of Cellular Nutrients Under Starvation Conditions As Well As The Normal Turnover Of Cytosolic Components. Beclin-1, A Principal Regulator Of Autophagosome Formation, Is In Turn Regulated By Ambra1. Ambra1 Associates With Beclin-1 Through A Region Near Its Center As Determined By Yeast Two-Hybrid Assay. Null Mutations In This Gene In Mice Resulted In Embryonic Lethality With Severe Neural Tube Defects Associated With Autophagy Impairment, Accumulation Of Ubiquitinated Proteins, Unbalanced Cell Proliferation And Excessive Apoptotic Death. Furthermore, Down-Regulation Of Ambra1 In Cultured Cells Though Rna Interference Decreased The Level Of Rapamycin- And Nutrient Starvation-Induced Autophagy. Multiple Isoforms Of Ambra1 Are Known To Exist.
純化方法 Affinity chromatography purified via peptide column
Autophagy/beclin-1 Regulator 1 (AMBRA1) (C-Term) 抗體目標詳細情況
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別名 Ambra1
背景 (CT) Autophagy Regulating Protein
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Autophagy/beclin-1 Regulator 1 (AMBRA1) (C-Term) 抗體使用細節(jié)
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應用備注 Ambra1 antibody can be used for the detection of Ambra1 by Western blot at 1 - 2?μg/mL
限制 For Research Use only
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注意事項 As with all antibodies care should be taken to avoid repeated freeze thaw cycles.
Antibodies should not be exposed to prolonged high temperatures.
儲存條件 4 °C
儲存方法 Ambra1 antibody can be stored at 4 °C
有效期 12 monthsxy-8184R AVSD2富含半胱氨酸與表皮生長因子樣蛋白2抗體
xy-7745R CKAP2細胞骨架相關蛋白2/腫瘤和微管相關蛋白抗體
xy-7744R CHMP4B+CHMP4C染色質修飾蛋白4B(4C)抗體
xy-3032R phospho-c-Abl (Tyr412)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-3041R phospho-c-Abl (Tyr226)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-3042R phospho-c-Abl (Tyr185)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-5053R CSNK1G2酪蛋白激酶1γ2抗體
xy-2389R Coxsackie Adenovirus Receptor柯薩奇病毒蛋白受體B抗體
xy-5996R CDC4腫瘤抑制因子FBW7抗體
xy-5997R Cell adhesion molecule 4細胞粘附分子4抗體
xy-5995R CAMTA1鈣調蛋白結合轉錄激活因子1抗體
xy-6518R CDK5RAP3周期素依賴性激酶5激活結合蛋白C53抗體
xy-6519R CENPH著絲粒蛋白H抗體
xy-6042R Cystatin E半胱氨酸蛋白酶抑制劑6抗體
xy-6024R CA10碳酸酐酶相關蛋白/腦蛋白10抗體
xy-2615R IL-18R alpha/CD218a白細胞介素-18受體α鏈抗體
xy-3778R CTCF轉錄阻抑蛋白CTCF抗體
xy-3786R CD1aT淋巴細胞CD1抗體
xy-4000R Phospho-CHK2 (ser19)磷酸化細胞周期檢測點激酶2抗體
xy-2932R Clathrin heavy chain網格蛋白重鏈抗體
xy-3845R CD168透明質酸介導細胞游走受體抗體
xy-9804R C2orf242號染色體開放閱讀框24抗體
xy-9809R C2orf602號染色體開放閱讀框60抗體
xy-5248R phospho-CDK7 (Thr170)磷酸化周期素依賴性激酶7抗體
xy-5249R Phospho-CDK9 (Thr29)磷酸化周期素依賴性激酶9抗體
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