CCNT1 抗體

抗原
Cyclin T1 (CCNT1)
別名 CG6292, Dmcyclin T, DmelCG6292, ORE-14, P-TEFb, anon-74EFc, dT, p124, Cyclin-T1, ccnt, cyct1, CCNT, CYCT1, HIVE1, 2810478G24Rik, AI115585, CycT1, fi75b02, si:dkey-18f23.10, wu:fi75b02
抗原表位
其他選擇 AA 253-281, Center
Internal Region(11),AA 256-285 (8),C-Term (5),N-Term (3),AA 1-726 (1),AA 250-300 (1),AA 253-281 (1),AA 321-420 (1),AA 325-375 (1),AA 425-475 (1),AA 625-675 (1),Middle Region (1)
適用
其他選擇 Human, Murine
Human(35),Murine (15),Rat ((Rattus)) (12),Bovine (2),Dog (Canine) (2),Pig (Porcine) (2),Xenopus laevis (2),Zebrafish (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(33),Mouse (2)
克隆類型 (克隆位點)
多克隆 (RB19562)
標記
其他選擇 非結合性
APC(1),Alkaline Phosphatase (AP) (1),Biotin (1),FITC (1),HRP (1),PE (1)
應用范圍
其他選擇 Western Blotting (WB), Flow Cytometry (FACS)
Western Blotting (WB)(34),ELISA (17),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11),Immunoprecipitation (IP) (10),Flow Cytometry (FACS) (9),Immunohistochemistry (IHC) (7),Immunofluorescence (IF) (5),Enzyme Immunoassay (EIA) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunoassay (IA) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1),Proximity Ligation Assay (PLA) (1)
[Pubmed] 3 references available
規(guī)格 400 μL
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至13個工作日

CCNT1 抗體

產品細節(jié)

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產品細節(jié)

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免疫原 This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 AA from the Central region of human CCNT1.
克隆位點 RB19562
亞型 Ig
特異性 This CCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the Central region of human CCNT1.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標詳細情況

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目標詳細情況

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別名 CCNT1
背景 CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
Synonyms: Cyclin-T1,CCNT1,
分子量 80685 DA
基因ID 904
NCBI Accession NP_001231
UniProt O60563
研究領域 Signaling, Phospho-specific antibodies, Protein Modifications, Cell Cycle, Transcription Factors, Cell Structure

使用細節(jié)

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使用細節(jié)

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應用備注 WB = 1:1000, FACS = 1:10-50
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.35 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months

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