NBN抗體

抗原
Nibrin (NBN)
別名 NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95, Nbs1, im:6911679, zgc:194152
抗原表位
其他選擇 C-Term, AA 602-630
pSer343(39),C-Term (20),pSer278 (9),N-Term (8),AA 645-755 (7),AA 609-638 (6),Internal Region (6),AA 341-345 (3),AA 704-754 (3),AA 467-615 (2),AA 625-675 (2),AA 645-754 (2),AA 701-751 (2),Ser343 (2),pSer432 (2),AA 1-705 (1),AA 225-274 (1),AA 251-300 (1),AA 310-359 (1),AA 331-380 (1),AA 337-350 (1),AA 350-400 (1),AA 420-774 (1),AA 425-475 (1),AA 431-480 (1),AA 602-630 (1),Pro461 (1),Thr11 (1),Thr115 (1),Thr337 (1)
適用
其他選擇 Human
Human(204),Rat ((Rattus)) (55),Murine (41),Chicken (12),Bovine (12),Dog (Canine) (12)
宿主
其他選擇 Rabbit
Rabbit(162),Mouse (46)
克隆類型 (克隆位點(diǎn))
多克隆 (RB19072)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(5),FITC (4),HRP (3),APC (2),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Alkaline Phosphatase (AP) (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),PE (2)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
Western Blotting (WB)(185),ELISA (73),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (43),Immunofluorescence (IF) (38),Immunohistochemistry (IHC) (27),Immunoprecipitation (IP) (23),Immunocytochemistry (ICC) (21),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Flow Cytometry (FACS) (11),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (5),Enzyme Immunoassay (EIA) (4),Fluorescence Microscopy (FM) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (2),Proximity Ligation Assay (PLA) (1)
[Pubmed] 3 references available
規(guī)格 400 μL
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NBN抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 AA from the C-terminal region of human NBN.
克隆位點(diǎn) RB19072
亞型 Ig
特異性 This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 609-638 amino acids from the C-terminal region of human NBN.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 NBN
背景 Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Synonyms: NBN,Nibrin,NBS, NBS1, P95
分子量 84959 DA
基因ID 4683
NCBI Accession NP_002476
UniProt O60934
研究領(lǐng)域 Phospho-specific antibodies, Protein Modifications, Cell Cycle, Chromatin, Signaling, Cell Structure

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應(yīng)用備注 WB = 1:1000, IF = 1:10-50, FACS = 1:10-50
限制 For Research Use only

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狀態(tài) Liquid
濃度 0.27 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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