PCDHA10抗體

抗原
Protocadherin alpha 10 (PCDHA10)
別名 CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10, Cnr3, Cnr8, Crnr3, Crnr8, Pcdha14, rCNRv10
抗原表位
其他選擇 N-Term
N-Term(9),AA 182-291 (7),AA 770-798 (7),C-Term (6),AA 182-290 (2),AA 21-262 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Human
Human(40),Murine (18),Rat ((Rattus)) (18),Chicken (14),Dog (Canine) (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(29),Mouse (11)
克隆類型
多克隆
標記
其他選擇 非結合性
Biotin(3),FITC (3),HRP (3),PE (3),APC (2),Alkaline Phosphatase (AP) (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(30),ELISA (16),Flow Cytometry (FACS) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (IHC) (6),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6),Immunoassay (IA) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

PCDHA10抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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免疫原 Synthetic peptide directed towards the N terminal of human PCDHA10
序列 DKDKFPVLVL RKLLDREENP QLKLLLTATD GGKPEFTGSV SLLILVLDAN
預測反應 Rat : 100 %, Dog : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against PCDHA10. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標詳細情況

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目標詳細情況

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別名 PCDHA10
背景 This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
分子量 73 kDa
基因ID 56139
NCBI Accession NM_031860, NP_114066
UniProt A1L493
研究領域 Signaling

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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 685 AA

限制 For Research Use only

貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

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