SEMA6D抗體

抗原
Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D)
別名 zgc:112012, si:ch211-278n20.1, wu:fi06a12, wu:fi76a10, zgc:56170, 1110067B02Rik, AA409156, D330011G23, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6, mKIAA1479
抗原表位
其他選擇 N-Term
N-Term(13),AA 18-48 (7),Cytoplasmic Domain (4),AA 1-476 (2),AA 19-48 (2)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Bovine, Zebrafish (Danio rerio), Xenopus laevis, Human, Chicken
Human(30),Murine (20),Rat ((Rattus)) (17),Bovine (13),Dog (Canine) (13),Pig (Porcine) (12),Chicken (1),Xenopus laevis (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(29),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(21),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),ELISA (6),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Immunoassay (IA) (2)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

SEMA6D抗體

產(chǎn)品細(xì)節(jié)

引用 圖像 貯存及處理 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Synthetic peptide directed towards the N terminal of human SEMA6D
序列 VSFPEDDEPL NTVDYHYSRQ YPVFRGRPSG NESQHRLDFQ LMLKIRDTLY
預(yù)測反應(yīng) Bovine : 100 %, Chicken : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %, African clawed frog : 80 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against SEMA6D. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

引用 圖像 貯存及處理 使用細(xì)節(jié) 回頁首

目標(biāo)詳細(xì)情況

顯示 隱藏
別名 SEMA6D
背景 Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
分子量 52 kDa
基因ID 80031
NCBI Accession NP_079242, NM_024966
UniProt Q8NFY4
研究領(lǐng)域 Neurology

使用細(xì)節(jié)

引用 圖像 貯存及處理 目標(biāo)詳細(xì)情況 回頁首

使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 476 AA

限制 For Research Use only

貯存及處理

引用 圖像 使用細(xì)節(jié) 目標(biāo)詳細(xì)情況 回頁首

貯存及處理

顯示 隱藏
狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

xy-5263R phospho-CDH2 (Tyr820)磷酸化N-鈣粘附分子抗體
xy-5268R phospho-CDC27 (Thr244)磷酸化后期促進(jìn)復(fù)合蛋白3抗體
xy-5184R phospho-c-Abl(Tyr283)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-5183R phospho-c-Abl(Thr735)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-15341R C9orf759號染色體開放閱讀框75抗體
xy-0647R CD4CD4抗體
xy-2347R CD42b血小板糖蛋白GPIb抗體
xy-4098R CARM1蛋白精氨酸N甲基4抗體
xy-5285R phospho-CARM1(Ser228)磷酸化蛋白精氨酸N甲基4抗體
xy-5286R phospho-CDK6 (Tyr13)磷酸化周期素依賴性激酶6抗體
xy-4072R phospho-CBL2 (Tyr700)磷酸化原癌基因CBL2抗體
xy-5148R Cdc7細(xì)胞分裂周期蛋白7抗體
xy-5242R Phospho-cdc25A (Ser124)磷酸化細(xì)胞分裂周期蛋白25抗體
xy-4094R Cdc25B細(xì)胞分裂周期蛋白25B抗體
xy-5284R phospho-CD244(Tyr271)磷酸化CD244抗體
xy-12059R CACNG3神經(jīng)元電壓門控鈣通道γ3/L-type Ca++CP γ3抗體
xy-15170R C3orf253號染色體開放閱讀框25抗體
xy-5978R c-Myb轉(zhuǎn)錄激活因子MYB抗體
xy-2986R CATSPER陽離子通道精子相關(guān)蛋白1抗體
xy-13802R C1orf2221號染色體開放閱讀框222抗體
xy-15146R C2orf152號染色體開放閱讀框15抗體
xy-6520R CKAP4細(xì)胞骨架相關(guān)蛋白4抗體
xy-5873R CNDP1肌肽二肽酶1抗體
xy-6522R CKMT酸性線粒體肌酸激酶抗體
xy-6516R CA8碳酸酐酶相關(guān)蛋白8抗體
xy-6517R CACNB1鈣通道電壓依賴性β1蛋白抗體
xy-6526R CD39L4原癌基因CD39樣蛋白4抗體
xy-5881R COL20A1膠原樣蛋白抗體
xy-5959R CASC5腫瘤易感性候選基因5抗體
xy-6253R CAMKK2鈣調(diào)蛋白激酶激酶β抗體
xy-5930R Centaurin gamma 1中心體肌動蛋白γ1/增強型PI3K蛋白抗體
xy-5963R CDCA7L細(xì)胞分裂周期相關(guān)蛋白JPO2抗體
xy-5802R Caspase 2半胱胺酸蛋白酶-2抗體
xy-15278R C7orf637號染色體開放閱讀框63抗體
xy-6239R CD2BP3CD2結(jié)合蛋白3抗體
xy-5882R CTHRC1膠原三股螺旋重復(fù)蛋白1抗體
xy-15115R c20orf7220號染色體開放閱讀框72抗體
xy-6549R C2orf62號染色體開放閱讀框6抗體
xy-5880R CDCP1CD318抗體