CSF2RA抗體

抗原
Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA)
別名 CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, Csfgmra, GM-CSF-Ra, GM-CSFR
抗原表位
其他選擇 AA 1-320
C-Term(11),AA 1-320 (9),AA 366-394 (9),AA 1-400 (4),Internal Region (4),AA 103-264 (2),N-Term (2),AA 204-360 (1),AA 28-112 (1),AA 379-396 (1)
適用
其他選擇 Human
Human(77),Murine (5)
宿主
其他選擇 Rabbit
Rabbit(47),Mouse (35)
克隆類型
多克隆
標記
其他選擇 非結(jié)合性
Biotin(8),FITC (7),PE (6),APC (1),Alkaline Phosphatase (AP) (1),HRP (1)
zui低檢測濃度 0.0049 ng/well
應用范圍
其他選擇 ELISA
Western Blotting (WB)(52),Flow Cytometry (FACS) (31),ELISA (29),Immunohistochemistry (IHC) (10),Immunocytochemistry (ICC) (6),Immunoprecipitation (IP) (6),Immunohistochemistry (Frozen Sections) (IHC (fro)) (5),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5),Immunoassay (IA) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Functional Studies (Func) (1),Immunohistochemistry (Acetone-fixed) (IHC (af)) (1),Neutralization (Neut) (1),Proximity Ligation Assay (PLA) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

CSF2RA抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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亞型 IgG
特異性 Human CD116 / GM-CSFR
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human CD116 / GM-CSFR (rh GM-CSFR, NP_034100.2, Met 1-Gly 320). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標詳細情況

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目標詳細情況

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別名 CSF2RA
背景 CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD116/GM-CSFR is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. CD116/GM-CSFR is found in the pseudoautosomal region (PAR) of the X and Y chromosomes.
NCBI Accession NP_034100.2
研究領域 Immunology

使用細節(jié)

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使用細節(jié)

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應用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human CD116. The detection limit for Human CD116 is 0.0049 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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