CXCL9 抗體

抗原
gamma-Interferon-Induced Monokine (CXCL9)
別名 CMK, Humig, MIG, SCYB9, crg-10, BB139920, Mig, MuMIG, Scyb9
抗原表位
其他選擇 AA 23-125
AA 23-125(14),AA 102-132 (6),AA 22-126 (5),C-Term (5),Middle Region (2),N-Term (2),AA 23-126 (1),AA 61-75 (1),Internal Region (1)
適用
其他選擇 Human
Human(68),Murine (35),Bovine (14),Pig (Porcine) (14),Rat ((Rattus)) (14)
宿主
其他選擇 Rabbit
Rabbit(74),Mouse (11),Goat (3),Chicken (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(12),FITC (6),HRP (5),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),His tag (1),PE (1)
zui低檢測濃度 0.00975 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(68),ELISA (60),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (17),Immunohistochemistry (IHC) (13),Immunocytochemistry (ICC) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Neutralization (Neut) (8),Enzyme Immunoassay (EIA) (5),Functional Studies (Func) (5),Immunohistochemistry (Frozen Sections) (IHC (fro)) (5),Immunofluorescence (IF) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Blocking Antibody (Inhibition) (1),Flow Cytometry (FACS) (1),Immunoassay (IA) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

CXCL9 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
亞型 IgG
特異性 Human CXCL9 / MIG
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human CXCL9 / MIG (rh CXCL9 / MIG, Q07325, Thr 23-Thr 125). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 CXCL9
背景 Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined, however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. Experiment data represent novel mechanisms by which tumour cells in melanoma metastases might use the chemokine-expressing endothelium to leave the tumour and eventually to form additional metastases at distinct sites. Experiment results also improved that CXCL9/MIG plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9/MIG, and recipient CD4 lymphocytes are necessary for sustained CXCL9/MIG production and CAV development in this model. Neutralization of the chemokine CXCL9/MIG may have therapeutic potential for the treatment of chronic rejection after heart transplantation.
UniProt Q07325
研究領(lǐng)域 Cytokines

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CXCL9. The detection limit for Human CXCL9 is approximay 0.00975 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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