MESDC2抗體

抗原
Mesoderm Development Candidate 2 (MESDC2)
別名 MGC115616, MESDC2, BOCA, MESD, 2210015O11Rik, AW537813, mKIAA0081, mesd, msd, zgc:158636
抗原表位
其他選擇 AA 34-230
C-Term(9),AA 203-234 (8),AA 34-230 (5),AA 206-234 (2),AA 1-234 (1),AA 30-224 (1)
適用
其他選擇 Human
Human(20),Murine (3),Mammalian (2),Rat ((Rattus)) (2)
宿主
其他選擇 Rabbit
Rabbit(19),Mouse (3),Sheep (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
APC(1),Alkaline Phosphatase (AP) (1),Biotin (1),FITC (1),HRP (1),PE (1)
zui低檢測(cè)濃度 0.00975 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(22),ELISA (14),Immunohistochemistry (IHC) (11),Immunocytochemistry (ICC) (6),Immunofluorescence (IF) (4),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2),Immunostaining (IS) (2),Enzyme Immunoassay (EIA) (1),Immunoassay (IA) (1),Immunoprecipitation (IP) (1)
[Pubmed] 3 references available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)

MESDC2抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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亞型 IgG
特異性 Human MESDC2 / MESD
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human MESDC2 (rh MESDC2, NP_055969.1, Ala 34-Lys 230). Total IgG was purified by Protein A affinity chromatography .
純化方法 Affinity Purified
過(guò)濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 MESDC2
背景 LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN- 61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
NCBI Accession NP_055969.1
研究領(lǐng)域 Lineage Markers

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human MESDC2. The detection limit for Human MESDC2 is approximay 0.00975 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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