STAP2抗體

抗原
Signal Transducing Adaptor Family Member 2 (STAP2)
別名 BKS, AW049765, STAP-2
適用
其他選擇 Human
Human(40),Murine (2),Rat ((Rattus)) (2)
宿主
其他選擇 Rabbit
Rabbit(25),Goat (14),Mouse (1)
克隆類型
多克隆
標記
其他選擇 Cy5.5
Biotin(2),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy7 (1),PE (1)
應用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Western Blotting (WB)(32),ELISA (16),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14),Immunohistochemistry (IHC) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (9),Enzyme Immunoassay (EIA) (4),Immunocytochemistry (ICC) (2),Immunofluorescence (IF) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2)
規(guī)格 100 μL
發(fā)貨至 中國 (更改)

STAP2抗體

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產(chǎn)品細節(jié)

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免疫原 KLH conjugated synthetic peptide derived from human STAP2
亞型 IgG
純化方法 purified by Protein A

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別名 STAP2
背景 Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
研究領域 Chromatin and Nuclear Signaling, Innate Immunity

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應用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說明

Excitation / Emission wavelength: 675nm / 694nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C

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