SCIMP抗體

抗原
SLP Adaptor and CSK Interacting Membrane Protein (SCIMP)
別名 C17orf87, UNQ5783, A430084P05Rik
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(15),Murine (11),Rat ((Rattus)) (11)
宿主
其他選擇 Rabbit
Rabbit(11),Mouse (4)
克隆類(lèi)型
多克隆
標(biāo)記
其他選擇 Cy5.5
Alexa Fluor 350(1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Biotin (1),Cy3 (1),Cy5 (1),Cy7 (1),FITC (1),HRP (1)
應(yīng)用范圍
其他選擇 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
Immunofluorescence (Paraffin-embedded Sections) (IF (p))(9),Western Blotting (WB) (7),Flow Cytometry (FACS) (3),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Immunoprecipitation (IP) (3),Immunocytochemistry (ICC) (2),Immunoassay (IA) (1),Immunofluorescence (IF) (1)
規(guī)格 100 μL
發(fā)貨至 中國(guó) (更改)

SCIMP抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 KLH conjugated synthetic peptide derived from human C17orf87
亞型 IgG
交叉反應(yīng) Murine, Rat ((Rattus))
純化方法 purified by Protein A

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目標(biāo)詳細(xì)情況

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別名 C17orf87
背景 C17orf87 (chromosome 17 open reading frame 87) is a 145 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

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使用細(xì)節(jié)

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應(yīng)用備注 IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator.
說(shuō)明

Excitation / Emission wavelength: 675nm / 694nm

限制 For Research Use only

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C

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