INCENP抗體

抗原
Inner Centromere Protein Antigens 135/155kDa (INCENP)
別名 INCENP, LOC572121, 2700067E22Rik, AU019509, C130081E20, C77457
抗原表位
其他選擇 AA 369-583
AA 325-400(6),C-Term (2),AA 300-400 (1),AA 369-583 (1),AA 834-918 (1),AA 884-901 (1),Ala841 (1),N-Term (1),Pro240 (1)
適用
其他選擇 Human
Human(17),Murine (1)
宿主
其他選擇 Mouse
Rabbit(14),Mouse (3)
克隆類型 (克隆位點)
單克隆 (3D2)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(1),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1),HRP (1)
應(yīng)用范圍
其他選擇 ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Immunocytochemistry (ICC)(12),Western Blotting (WB) (9),Immunofluorescence (IF) (6),ELISA (5),Flow Cytometry (FACS) (5),Immunohistochemistry (IHC) (5),Immunoprecipitation (IP) (3)
[Pubmed] 3 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 24至29個工作日

INCENP抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Purified recombinant fragment of human INCENP (AA 369-583) expressed in E. coli.
克隆位點 3D2
亞型 IgG1
純化方法 Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 INCENP
背景 In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins. The constitutive proteins include CENPA (centromere protein A, MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE (MIM 117143), MCAK (MIM 604538), KID (MIM 603213), cytoplasmic dynein (e. g. , MIM 600112), CliPs (e. g. , MIM 179838), and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-mηphase. During ophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis
分子量 105.4 kDa
基因ID 3619
研究領(lǐng)域 Chromatin and Nuclear Signaling, Cell Cycle

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應(yīng)用備注 Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
緩沖液 PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
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