AOC2抗體

抗原
Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2)
別名 DAO2, RAO, Aoc2, Rao, aoc2, AOC2, AOC3
抗原表位
其他選擇 Middle Region
Internal Region(4),AA 1-756 (3),Middle Region (2),AA 169-268 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Bovine, Zebrafish (Danio rerio), Xenopus laevis, Human, Chicken
Human(13),Murine (4),Bovine (2),Dog (Canine) (2),Rat ((Rattus)) (2),Chicken (1),Xenopus laevis (1),Zebrafish (Danio rerio) (1)
宿主
其他選擇 Rabbit
Rabbit(10),Mouse (3)
克隆類型
多克隆
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(13),Immunoassay (IA) (3),ELISA (1),Immunoprecipitation (IP) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日

AOC2抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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免疫原 Synthetic peptide directed towards the middle region of human AOC2
序列 AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN
預(yù)測(cè)反應(yīng) Bovine : 100 %, Dog : 100 %, Human : 100 %, Rabbit : 100 %, Mouse : 90 %, Pig : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against AOC2. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 AOC2
背景 Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
分子量 84 kDa
基因ID 314
NCBI Accession NM_009590, NP_033720
UniProt O75106
研究領(lǐng)域 Neurology

使用細(xì)節(jié)

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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說(shuō)明

Antigen size: 756 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 50 μL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C

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