KDM3A抗體

抗原
Lysine (K)-Specific Demethylase 3A (KDM3A)
別名 tsga, jmjd1, jhdm2a, jhmd2a, jmjd1a, KDM3A, JMJD1A, kdm3a, JHDM2A, JHMD2A, JMJD1, TSGA, 1700105C21Rik, C230043E16Rik, JHDM2a, Jmjd1, Jmjd1a, KDM2A, TGSA, Tsga, mKIAA0742
抗原表位
其他選擇 N-Term
C-Term(7),N-Term (7),AA 983-1017 (6),AA 250-400 (5),Internal Region (4),AA 1025-1075 (1),AA 1181 (1),AA 1271-1321 (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(53),Murine (18),Rat ((Rattus)) (12),Chicken (1),Bovine (1),Dog (Canine) (1),Fruit Fly (Drosophila melanogaster) (1),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(34),Mouse (19)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
APC(1),Alkaline Phosphatase (AP) (1),Biotin (1),DyLight 488 (1),DyLight 550 (1),DyLight 650 (1),FITC (1),HRP (1),PE (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(52),ELISA (31),Immunohistochemistry (IHC) (28),Immunofluorescence (IF) (16),Immunocytochemistry (ICC) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10),Immunoprecipitation (IP) (4),Enzyme Immunoassay (EIA) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2)
[Pubmed] 4 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

KDM3A抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 JMJD1A antibody was raised against a 16 amino acid peptide from near the amino terminus of human JMJD1A.
亞型 IgG
特異性 This antibody detects KDM3A / JHDM2A. It will not cross-react with JMJD1B or JMJD1C.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human, mouse, rat
純化方法 Peptide affinity chromatography

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 KDM3A / JHDM2A
背景 The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist.Synonyms: JMJD1, JMJD1A, JmjC domain-containing histone demethylation protein 2A, Jumonji domain-containing protein 1A, KIAA0742, Lysine-specific demethylase 3A, TSGA
基因ID 55818
NCBI Accession NP_060903
UniProt Q9Y4C1
研究領(lǐng)域 Chromatin and Nuclear Signaling, Transcription Factors

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA. Western blot: 1 - 2?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
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