NRTN抗體

抗原
Neurturin (NRTN)
別名 NRTN, NTN
抗原表位
其他選擇 AA 178-193
C-Term(10),AA 45-75 (6),Internal Region (5),AA 178-193 (4),AA 96-197 (2)
適用
其他選擇 Human
Human(62),Murine (20),Rat ((Rattus)) (14),Bovine (12),Dog (Canine) (12)
宿主
其他選擇 Rabbit
Rabbit(49),Goat (9),Mouse (4),Sheep (3)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(5),FITC (2),HRP (2),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(55),ELISA (31),Immunohistochemistry (IHC) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Enzyme Immunoassay (EIA) (6),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3),Neutralization (Neut) (3),Functional Studies (Func) (2),Blocking Antibody (Inhibition) (1),Blocking Reagent (BR) (1),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 4 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

NRTN抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 Neurturin antibody was raised against a peptide corresponding to amino acids 178 to 193 of human neurturin.
亞型 IgG
特異性 This antibody detects Neurturin.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human
純化方法 Peptide affinity chromatography

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

顯示 隱藏
別名 Neurturin
背景 Glial cell line-derived neurotrophic factor (GDNF) plays key roles in the control of vertebrate neuron survival and differentiation. A novel neurotrophic factor was recently cloned from human and mouse and designated neurturin. Physiological responses to neurturin (NTN) require the presence of receptor tyrosine kinase RET and a novel glycosylphosphatidylinositol linked receptor NTNRalpha. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently (3-8) and termed GDNFRb, Ret ligand 2 (RETL2) or TGF-Β-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently. NTN binds to and forms a complex with GFRalpha-2 and the Ret PTK and activates the RET receptor tyrosine kinase pathway. Both NTN and GDNF can activate the MAP kinase and phosphatidylinositol 3-kinase pathways and play a critical role in the development of many neuronal populations. Neurturin and GDNF define a new family of neurotrophic factors.Synonyms: NRTN
基因ID 4902
NCBI Accession NP_004549
UniProt Q99748
研究領(lǐng)域 Neurology

使用細(xì)節(jié)

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使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
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