TACR3 抗體

抗原
Tachykinin Receptor 3 (TACR3)
別名 HH11, NK-3R, NK3R, NKR, TAC3RL, Nk3r, Nkr, Tac3r, Nmkr
抗原表位
其他選擇 Center
C-Term(19),N-Term (11),AA 405-435 (7),Middle Region (5),Internal Region (3),AA 406-435 (2),Extracellular Domain (2),AA 385-434 (1),AA 401-450 (1),AA 401-465 (1),Center (1),Cytoplasmic Domain (1),Pro434 (1)
適用
其他選擇 Human, Murine
Human(75),Murine (46),Rat ((Rattus)) (41),Dog (Canine) (25),Chicken (24),Bovine (24),Guinea Pig (24),Pig (Porcine) (24),Horse (Equine) (4),Gerbil (1)
宿主
其他選擇 Rabbit
Rabbit(79)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),APC (1),Alkaline Phosphatase (AP) (1),PE (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(47),ELISA (27),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (19),Immunofluorescence (IF) (10),Immunohistochemistry (IHC) (10),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunohistochemistry (Frozen Sections) (IHC (fro)) (3),Enzyme Immunoassay (EIA) (1),Immunocytochemistry (ICC) (1)
[Pubmed] 4 references available
規(guī)格 0.1 mg
發(fā)貨至 中國 (更改)
發(fā)貨時間 29至35個工作日

TACR3 抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 NK3R antibody was raised against a 18 amino acid peptide from near the center of human NK3R.
亞型 IgG
特異性 This antibody detects Tachykinin receptor 3 (TACR3) at center. It does not recognize NK1R or NK2R.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human, mouse
純化方法 Peptide affinity chromatography

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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背景 The tachykinins are a family of small peptides that include the neurotransmitters substance P, neurokinin A, and neurokinin B, which can act on three related but distinct seven transmembrane G-proteins coupled receptors, albeit at different concentrations. The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system. It is likely these signals lead to the release of vasopressin and oxytocin into the circulation. NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice. Although it has been suggested that NK3R plays a role in the regulation of vagal afferent relay neurons, it is likely that these receptors are activated by substance P or neurokinin A, as the airway nerves do not express neurokinin B.Synonyms: NK-3 receptor, NK-3R, NK3R, NKR, Neurokinin B receptor, Neuromedin-K receptor, TAC3R
基因ID 6870
NCBI Accession NP_001050
UniProt P29371
研究領(lǐng)域 Receptors, Neurotransmitters

使用細(xì)節(jié)

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使用細(xì)節(jié)

顯示 隱藏
應(yīng)用備注 ELISA. Western blot: 0.5 - 1?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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貯存及處理

顯示 隱藏
緩沖液 PBS containing 0.02?% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Avoid repeated freezing and thawing.
儲存條件 4 °C/-20 °C

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