5-羥色胺受體3D+3E抗體

英文名稱 5HT3D + 5HT3E Receptor
中文名稱 5-羥色胺受體3D+3E抗體
別    名 5 HT3 D; 5 HT3 E; 5 HT3c1; 5 HT3D; 5-HT3-D; 5-HT3D; 5 HT3E; 5 hydroxytryptamine (serotonin) receptor 3 family member D; 5-hydroxytryptamine receptor 3D; 5 hydroxytryptamine (serotonin) receptor 3 family member E; 5 hydroxytryptamine receptor 3 subunit D; 5 hydroxytryptamine receptor 3 subunit E; 5 hydroxytryptamine receptor 3D; 5 hydroxytryptamine receptor 3E; 5HT3D; HTR3D; HTR3E; MGC119636; MGC119637; MGC120035; MGC120036; MGC120037; Serotonin 5 HT 3D receptor; Serotonin receptor 3D; Serotonin receptor 3E; 5HT3D_HUMAN; 5HT3E_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human 5HT3D + 5HT3E Receptor
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Serotonin is a monoamine neurotransmitter that is made in serotonergic neurons in the CNS (central nervous system) and is important in the regulation of mood, sleep, vomiting, sexuality and appetite. 5-HT3 (5-hydroxytryptamine-3) receptor is the only ligand-gated ion channel within the family of serotonin receptors. It is composed of five subunits consisting of SR-3A, SR-3B, HTR3C, HTR3D and HTR3E. HTR3D (5-hydroxytryptamine receptor 3D), also known as Serotonin receptor 3D, is a 454 amino acid multi-pass membrane protein that is one components of the pentaheteromeric complex that forms the 5-HT3 receptor. HTR3D must be co-expressed with SR-3A to form a functional 5-HT3 receptor complex on the plasma membrane. Until it is complexed with SR-3A, HTR3D is localized within the endoplasmic reticulum. Expression of HTR3D is restricted to kidney, colon and liver. There are three different isoforms of HTR3D that are expressed as a result of alternative splicing events.

Function:
5HT3D Receptor and 5HT3E Receptor are receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The receptors form a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. 

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xy-15453R    HEMK2Hemk甲基轉(zhuǎn)移酶家族2號蛋白抗體
xy-15454R    HENMT1HEN1甲基轉(zhuǎn)移酶同源蛋白1抗體
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xy-15419R    HBQ1血紅蛋白theta亞型1抗體
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xy-15428R    HCP1血紅素轉(zhuǎn)運蛋白1抗體
xy-15429R    HCP5血紅素轉(zhuǎn)運蛋白5抗體
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