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神經(jīng)細胞囊泡循環(huán)蛋白1抗體

參   考   價: 80

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

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更新時間:2018-06-05 09:47:55瀏覽次數(shù):547次

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神經(jīng)細胞囊泡循環(huán)蛋白1抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.

神經(jīng)細胞囊泡循環(huán)蛋白1抗體

英文名稱 Synaptogyrin 1
中文名稱 神經(jīng)細胞囊泡循環(huán)蛋白1抗體
別    名 SNG1_HUMAN;Synaptogyrin-1;Syngr1.

說 明 書 0.2ml  
研究領域 細胞生物  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synaptogyrin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal isoforms (Synaptogyrin-1 and -3) and one ubiquitous isoform (Synaptogyrin-2). Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as cellugyrin, has a tyrosine phosphorylated C-terminal cytoplasmic tail and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. Synaptogyrin-4 is a 234 amino acid protein encoded by the SYNGR4 gene.

Function:
Involved in the regulation of short-term and long-term synaptic plasticity.

Subcellular Location:
Membrane; Multi-pass membrane protein. Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Similarity:
Belongs to the synaptogyrin family.
Contains 1 MARVEL domain.
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