神經(jīng)突觸素13抗體

英文名稱 Syntaxin 13
中文名稱 神經(jīng)突觸素13抗體
別    名 Syntaxin13; Syntaxin 13; Syntaxin-13; Syx13; Syx 13; Syx-13; CG11278; CT31479; Dm Syx13; ff16; l(3)01470; STX12_RAT.
  
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from rat Syntaxin 13
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Syntaxin 13 is an integral membrane protein that belongs to the t-SNARE family, a group of proteins involved in protein transport. Confocal immunofluoresence and electron microscopy studies have shown that syntaxin 13 is primarily localized to tubular early and recycling endosomes, where it colocalizes with transferrin receptor, and it is also localized in endosomal vacuoles. Syntaxin 13 has been found to be expressed in all tissues, with higher levels of the protein found in brain, lung, spleen, thymus and testes. Immunoprecipitation studies show that syntaxin 13 complexes with beta-SNAP, VAMP2/3, and SNAP25. The binding of this complex to alpha-SNAP and NSF is terminated in the presence of ATP. These results suggest that syntaxin 13 is a SNARE protein which mediates the recycling protein flow through tubulo vesicular recycling endosomes.

Function:
SNARE that acts to regulate protein transport between endosomes and the trans-Golgi network (By similarity). The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro).

Subunit:
Associates with the BLOC-1 complex. Interacts with BLOC1S6 (By similarity). Interacts with NAPA and SNAP23. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A.

Subcellular Location:
Endosome membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Endomembrane system; Single-pass type IV membrane protein; Cytoplasmic side (Potential).

Tissue Specificity:
Ubiquitous. Highly expressed in brain.xy-7753R    KLHL9kelch樣蛋白9抗體
xy-7804R    KIF15驅動蛋白家族成員15抗體
xy-7808R    KNTC1著絲點關聯(lián)蛋白1抗體
xy-7806R    KLHDC5kelch樣蛋白5抗體
xy-7805R    KIFC1驅動蛋白家族成員C1抗體
xy-7807R    KLHL22Kelch樣蛋白22抗體
xy-6671R    KCND1電壓門控鉀通道Kv4.1抗體
xy-6674R    KCNK3酸敏感鉀離子通道蛋白3抗體
xy-2925R    KlothoKlotho多肽蛋白抗體
xy-6675R    KCNN4鈣激活鉀通道蛋白4抗體
xy-8049R    KLHL23Kelch樣蛋白23抗體
xy-8044R    KBTBD10BTB-kelch蛋白家族10抗體
xy-8045R    KBTBD4BTB-kelch蛋白家族4抗體
xy-8050R    KLHL24Kelch樣蛋白24抗體
xy-8048R    KLHL21Kelch樣蛋白21抗體
xy-8051R    KLHL25Kelch樣蛋白25抗體
xy-11026R    Kinesin驅動蛋白KNS1抗體
xy-11033R    KIF1B驅動蛋白家族成員1B抗體
xy-7851R    katanin p80劍蛋白p80抗體
xy-6435R    KIRREL1腎病樣蛋白1抗體
xy-11670R    SETDB1組蛋白H3K9甲基轉移酶4抗體
xy-11661R    KCNE3鉀離子通道蛋白家族成員3抗體
xy-6947R    Keratin82角蛋白82抗體
xy-9696R    C20orf1920號染色體開放閱讀框19抗體
xy-11054R    Keratocan細胞角膜蛋白多糖抗體
xy-9560R    KRCC1含賴氨酸卷曲螺旋蛋白1抗體
xy-4812R    Prostate Specific Antigen激肽釋放酶3/舒血管素3抗體
xy-9526R    KLF1, 2, 4上皮鋅指蛋白1, 2, 4抗體
xy-1064R    KLF4腸道內富含的Kruppel樣因子/上皮鋅指蛋白4抗體
xy-3549R    KSR1Ras信號轉導KSR1蛋白抗體
xy-0225M    KLH血藍蛋白抗體
xy-8546R    KRIT1腦海綿狀血管畸形蛋白1抗體
xy-9716R    KBPKBP蛋白抗體
xy-1094R    kappa Opioid receptorkappa型阿片受體抗體
xy-7688R    Kininogen-1 heavy chain激肽原1重鏈抗體