單鏈DNA結(jié)合蛋白相互作用蛋白1

英文名稱 SOSSC
中文名稱 單鏈DNA結(jié)合蛋白相互作用蛋白1
別    名 Chromosome 9 open reading frame 80; hSSBIP1; MISE; RP11-276E15.2; Sensor of single-strand DNA complex subunit C; Sensor of ssDNA subunit C; Single-stranded DNA-binding protein-interacting protein 1; SOSS C; SOSS complex subunit C; SOSS-C; SOSSC; SOSSC_HUMAN; SSB-interacting protein 1; Ssbip1; C9orf80.
  
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOSSC/C9orf80
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.xy-6154R    RAC1+RAC2GTP結(jié)合蛋白R(shí)AC1+RAC2抗體
xy-6176R    RAB8ras癌基因家族Rab8蛋白/原癌基因c MEL抗體
xy-6174R    RAB2ras癌基因家族Rab2抗體
xy-6179R    RAB3Aras癌基因家族Rab3a抗體
xy-6177R    RAB9ras癌基因家族Rab9蛋白抗體
xy-6178R    RAB20ras癌基因家族RAB20抗體
xy-6170R    RALA+RALBRas樣蛋白A+B抗體
xy-10145R    Rad51Rad51抗體
xy-12290R    RBMY1FRNA結(jié)合蛋白片段Y染色體家族蛋白2抗體
xy-12289R    RBMY1A1RNA結(jié)合蛋白片段Y染色體家族蛋白1抗體
xy-6358R    RNA polymerase IIIRNA聚合酶III抗體
xy-10118R    phospho-Ron (Tyr1238+Tyr1239)磷酸化原癌基因c-Met相關(guān)酪氨酸激酶抗體
xy-12294R    phospho-RUNX1(Ser303)磷酸化急性髓細(xì)胞白血病1蛋白抗體
xy-7121R    Rad23DNA修復(fù)蛋白R(shí)ad23抗體
xy-12261R    RTF1組織相容性復(fù)合物RTF1抗體
xy-1574R    RRM1核糖核苷酸還原酶1抗體
xy-9232R    RNF167環(huán)指蛋白167抗體
xy-2214R    Resistin抵抗素抗體
xy-3560R    RASGRF1Ras特異性鳥(niǎo)嘌呤核苷酸釋放因子1
xy-3554R    Rsk2核糖體S6激酶RSK2抗體
xy-3647R    RACK1受體激活蛋白激酶C1抗體
xy-3863R    ROR Gamma孤兒核受體抗體
xy-9163R    RNF17環(huán)指蛋白17抗體
xy-1264R    RSV呼吸道合胞病毒抗體
xy-4179R    RAD9細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-5642R    phospho-RAD9(Ser272)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-5655R    phospho-RAD9(Ser336)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-5656R    phospho-RAD9(Ser375)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-1483R    RBBP6增殖潛能相關(guān)蛋白抗體
xy-1480R    Rho CRhoC抗體
xy-9260R    RNF170環(huán)指蛋白170抗體