轉(zhuǎn)錄因子SOX-11蛋白抗體

英文名稱 SOX11
中文名稱 轉(zhuǎn)錄因子SOX-11蛋白抗體
別    名 SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.

說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SOX11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse (Collignon et al., 1996). These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution. SOX11 appears to be important in the developing nervous system (SOX11 expression is detected from 8.5 dpc through to 13.5 dpc, with a considerable increase in expression by 13.5 dpc). SOX11 expression is apparent in the somites,limbs,facial mesenchyme,kidney,lung of the fetal system.

Function:
Transcriptional activator.

Subcellular Location:
Nucleus.xy-0700R    NSBP1核小體結(jié)合蛋白1抗體
xy-11036R    Neurexin 1軸突蛋白1(Neurexin 1α)抗體
xy-11105R    Ninjurin 1神經(jīng)損傷誘導(dǎo)蛋白1抗體
xy-11106R    Ninjurin 2神經(jīng)損傷誘導(dǎo)蛋白2抗體
xy-6261R    NEK3絲氨酸/蘇氨酸蛋白激酶Nek3抗體
xy-5732R    NEK2中心體相關(guān)蛋白激酶Nek2抗體
xy-11435R    Neurogranin神經(jīng)顆粒素抗體
xy-11428R    Neuropeptide S神經(jīng)肽S抗體
xy-11429R    Neuropeptide S神經(jīng)肽S抗體
xy-11430R    NPSR1神經(jīng)肽S受體1/G蛋白偶聯(lián)受體154抗體
xy-11420R    NMUR1G蛋白偶聯(lián)受體66/神經(jīng)調(diào)節(jié)肽U受體1抗體
xy-11421R    NMUR2G蛋白偶聯(lián)受體FM4/神經(jīng)調(diào)節(jié)肽U受體2抗體
xy-11422R    Neuropeptide S神經(jīng)肽S抗體
xy-11409R    NR0B1腎上腺發(fā)育不全相關(guān)蛋白抗體
xy-7627R    NS5ATP9丙型肝炎病毒非結(jié)構(gòu)蛋白5A反式激活蛋白9抗體
xy-7074R    NoxaNoxa蛋白抗體
xy-7073R    NME5P53誘導(dǎo)細(xì)胞凋亡抑制蛋白抗體
xy-5526R    phospho-TrkB (Tyr705)磷酸化酪氨酸激酶B抗體
xy-5523R    phospho-NDEL1(Ser242)磷酸化中心粒蛋白Nudel抗體
xy-5524R    phospho-NDEL1(Thr219)磷酸化中心粒蛋白Nudel抗體
xy-3961R    NDUFS4線粒體復(fù)合物NDUFS4蛋白抗體
xy-3958R    NDUFA8NADH脫氫酶α家族8抗體
xy-3959R    NDUFV1NADH脫氫酶黃素蛋白1抗體
xy-3960R    NDUFV2NADH脫氫酶黃素蛋白2抗體
xy-3956R    NDUFA1NADH氧化還原酶輔酶1抗體
xy-8511R    NOD26膜內(nèi)在蛋白NOD26抗體
xy-8566R    Phospho-NMDAR2B (Tyr1474)磷酸化谷氨酸受體2B抗體
xy-8567R    Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252)磷酸化谷氨酸受體2A+2B抗體
xy-5271R    NEK6高度相似的細(xì)胞周期蛋白激酶NEK6抗體
xy-4839R    nonstructural protein 1A型流感病毒-NS1抗體（神經(jīng)氨酸酶1）
xy-10186R    NET1去甲腎上腺素轉(zhuǎn)運(yùn)蛋白/神經(jīng)遞質(zhì)去甲腎上腺素轉(zhuǎn)運(yùn)體抗體
xy-13071R    Phospho-eNOS (Ser1176)磷酸化一氧化氮合成酶3（內(nèi)皮型）抗體
xy-3552R    Nesfatin-1新的飽食分子蛋白抗體