快速發(fā)育生長因子同源蛋白2抗體

英文名稱 Sprouty 2
中文名稱 快速發(fā)育生長因子同源蛋白2抗體
別    名 hSPRY 2; hSPRY2; MGC23039; Sprouty homolog 2 (Drosophila); Sprouty homolog 2; Sprouty2; Spry 2; Spry2; SPY2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  神經(jīng)生物學(xué)  干細(xì)胞  生長因子和激素  血管內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Sprouty 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty 2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C terminus of the protein. Significant sequence divergence occurs at the N terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.

Function:
May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

Subunit:
Interacts with RAF1. xy-6557R    OCIAD2卵巢癌免疫反應(yīng)抗原抗體
xy-5714R    OVCA1卵巢癌相關(guān)基因1抗體
xy-5723R    OSGIN1氧化應(yīng)激誘導(dǎo)生長抑制因子1抗體
xy-6334R    ORP8氧化固醇結(jié)合蛋白8抗體
xy-11229R    OTUB1泛素特異性蛋白酶OTB1抗體
xy-11764R    OPA1視神經(jīng)萎縮相關(guān)蛋白1抗體
xy-15593R    OAZ1鳥氨酸脫羧酶抗酶1抗體
xy-11626R    OR5T1嗅覺受體家族5亞基1抗體
xy-1111R    Oct-3/Oct-4胚胎干細(xì)胞關(guān)鍵蛋白抗體
xy-0974R    Oxytetracycline土霉素抗體
xy-9750R    ANKRD45腫瘤/睪丸抗原117
xy-15594R    OAZ2鳥氨酸脫羧酶抗酶2抗體
xy-15595R    OAZ3鳥氨酸脫羧酶抗酶3抗體
xy-11520R    Orexin Prepro食欲素前體蛋白OX抗體
xy-7025R    Otoraplin纖維細(xì)胞源性蛋白
xy-6724R    OTC鳥氨酸氨基甲酰轉(zhuǎn)移酶抗體
xy-5901R    OS9OS-9蛋白抗體
xy-4147R    Cenexin1精子尾部結(jié)構(gòu)蛋白抗體
xy-5530R    phospho-ODF2(Ser796)磷酸化精子尾部結(jié)構(gòu)蛋白抗體
xy-3687R    OGG18-羥基鳥嘌呤DNA糖基化酶
xy-11629R    OR10J3嗅覺受體家族10亞基J3抗體
xy-11624R    OR2A4嗅覺受體家族2亞基4抗體
xy-11628R    OR5P3嗅覺受體家族5亞基3抗體
xy-9369R    ODF3B外致密纖維蛋白3B抗體
xy-4917R    Osteocalcin骨鈣蛋白/骨鈣素抗體
xy-9061R    ODZ3固生蛋白3抗體
xy-9406R    CT135腫瘤/睪丸抗原135抗體
xy-9407R    OIF骨誘導(dǎo)因子抗體
xy-11203R    OCT6八聚體結(jié)合轉(zhuǎn)錄因子6抗體
xy-11194R    OLIG2少突膠質(zhì)細(xì)胞轉(zhuǎn)錄因子2抗體
xy-0807R    Os05g0477200 protein水稻白葉枯病菌Os05g0477200蛋白抗體
xy-8506R    OSTM1骨硬化病相關(guān)跨膜蛋白1抗體
xy-9915R    Orosomucoid 2類粘蛋白2抗體
xy-0830R    Oct4胚胎干細(xì)胞關(guān)鍵蛋白抗體