絲氨酸/蘇氨酸激酶36融合同源蛋白抗體

英文名稱 STK36
中文名稱 絲氨酸/蘇氨酸激酶36融合同源蛋白抗體
別    名 FU antibody Fused homolog; KIAA1278; Serine/threonine kinase 36, fused homolog; STK36_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 144kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STK36
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.

Function:
Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia. xy-12121R    UNC80UNC80蛋白抗體
xy-9413R    TSPAN4四分子交聯(lián)體4抗體（四旋蛋白）
xy-4748R    TBX18轉(zhuǎn)錄因子Tbx18抗體
xy-7116R    TROVE-2干燥綜合征相關(guān)蛋白2抗體
xy-7118R    TRIP4甲狀腺激素受體相互作用蛋白4抗體
xy-12153R    TXLNBβ-taxilin蛋白抗體
xy-7660R    TFDP2轉(zhuǎn)錄因子E2F二聚體蛋白2抗體
xy-7654R    TIP30TIP30蛋白抗體
xy-6850R    TPST1酪蛋白硫酸轉(zhuǎn)移酶1抗體
xy-1197R    TLR5Toll樣受體5抗體
xy-7664R    TMUB1跨膜和泛素樣結(jié)構(gòu)域蛋白1抗體
xy-3422R    Phospho-TCTP(Ser46)磷酸化翻譯控制腫瘤蛋白抗體
xy-3424R    Phospho-TLK1(Ser695)磷酸化調(diào)節(jié)染色體組裝激酶1抗體
xy-2160R    Tumstatin腫瘤抑素抗體
xy-2671R    TBX3轉(zhuǎn)錄因子Tbx3抗體
xy-3463R    Phospho-TH (Ser31)磷酸化酪氨酸羥化酶抗體
xy-6065R    TCF3轉(zhuǎn)錄因子3抗體（螺旋環(huán)螺旋蛋白HE47）
xy-6066R    phospho-TCF3(Thr355)磷酸化轉(zhuǎn)錄因子3抗體
xy-4662R    phospho-TCF3 (Ser39)磷酸化轉(zhuǎn)錄因子3抗體
xy-3599R    Tbx21T細(xì)胞介導(dǎo)的轉(zhuǎn)錄調(diào)節(jié)因子Tbx21抗體
xy-3456R    Phospho-TrkA(Tyr496) +TrkB(Tyr516)磷酸化酪氨酸激酶A抗體
xy-3732R    Phospho-TrkA (Tyr785)+TrkB (Tyr816)磷酸化酪氨酸激酶A抗體
xy-3459R    Phospho-Tuberin (Ser1254)磷酸化馬鈴薯球蛋白(結(jié)節(jié)性硬化)抗體
xy-3437R    Phospho-Tyk2(Tyr1054 + Tyr1055)磷酸化非受體酪氨酸蛋白激酶2抗體
xy-3458R    Phospho-Troponin I(Ser23 + Ser24)磷酸化鈣調(diào)節(jié)蛋白-1抗體
xy-3415R    Phospho-TORC2 (Ser171)磷酸化CREB轉(zhuǎn)錄共激活因子TORC2抗體
xy-1511R    TRP2酪氨酸酶相關(guān)蛋白2抗體
xy-2441R    TWIST proteinTWIST蛋白抗體
xy-3462R    Phospho-Tyrosine Hydroxylase (Ser40)磷酸化酪氨酸羥化酶抗體
xy-10542R    Topoisomerase I拓普西異構(gòu)酶Ⅰ抗體
xy-13712R    TIN-Ag腎小管間質(zhì)腎炎抗原抗體
xy-13622R    TMEM176A跨膜蛋白176A抗體