單羧酸轉運蛋4抗體

英文名稱 MCT4
中文名稱 單羧酸轉運蛋4抗體
別    名 Monocarboxylate transporter 4; Slc16a3; Mct3; Mct4; MCT-4; Monocarboxylate transporter 3; solute carrier family 16 member 3; SLC16A3; MOT4_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  轉錄調節(jié)因子  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC16A3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]

Function:
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.xy-5526R    phospho-TrkB (Tyr705)磷酸化酪氨酸激酶B抗體
xy-5523R    phospho-NDEL1(Ser242)磷酸化中心粒蛋白Nudel抗體
xy-5524R    phospho-NDEL1(Thr219)磷酸化中心粒蛋白Nudel抗體
xy-3961R    NDUFS4線粒體復合物NDUFS4蛋白抗體
xy-3958R    NDUFA8NADH脫氫酶α家族8抗體
xy-3959R    NDUFV1NADH脫氫酶黃素蛋白1抗體
xy-3960R    NDUFV2NADH脫氫酶黃素蛋白2抗體
xy-3956R    NDUFA1NADH氧化還原酶輔酶1抗體
xy-8511R    NOD26膜內在蛋白NOD26抗體
xy-8566R    Phospho-NMDAR2B (Tyr1474)磷酸化谷氨酸受體2B抗體
xy-8567R    Phospho-NMDAR2A + 2B (Tyr1246 + Tyr1252)磷酸化谷氨酸受體2A+2B抗體
xy-5271R    NEK6高度相似的細胞周期蛋白激酶NEK6抗體
xy-4839R    nonstructural protein 1A型流感病毒-NS1抗體（神經氨酸酶1）
xy-10186R    NET1去甲腎上腺素轉運蛋白/神經遞質去甲腎上腺素轉運體抗體
xy-13071R    Phospho-eNOS (Ser1176)磷酸化一氧化氮合成酶3（內皮型）抗體
xy-3552R    Nesfatin-1新的飽食分子蛋白抗體
xy-4051R    Nectin 4脊髓灰質炎病毒受體相關蛋白4抗體
xy-2681R    NKp80細胞毒性受體NK-p80抗體
xy-2679R    CD112細胞粘附分子CD112抗體
xy-10233R    Nephrin腎小球細胞粘附分子受體抗體
xy-10444R    NR5A2/LRH1成纖維細胞核受體Nr5a2抗體
xy-1550R    NCX1鈉鈣交換蛋白1抗體
xy-2057R    NCX3鈉鈣交換蛋白3抗體
xy-2030R    NMDAR1天冬氨酸受體抗體
xy-2013R    phospho-Nrf2 (Ser40)磷酸化核因子2相關因子2(Ser40)抗體
xy-10420R    Nemo-like kinaseNemo樣激酶抗體
xy-10421R    Phospho-Nemo-like kinase (Thr298)磷酸化Nemo樣激酶抗體
xy-10402R    phospho-NIFK (Thr238)磷酸化NIFK抗體
xy-10401R    phospho-NIFK (Thr230)磷酸化NIFK抗體
xy-13693R    NCKAP5NCKAP5蛋白抗體
xy-13694R    NOSTRIN一氧化氮合酶轉運誘導抗體
xy-13656R    NSMAF中性鞘磷脂相關因子抗體
xy-15592R    NFIL3人白介素3介導核因子抗體
xy-13657R    NSP3SH2結構域蛋白3A抗體