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神經(jīng)突觸素1抗體

參   考   價: 80

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

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更新時間:2015-06-02 14:14:37瀏覽次數(shù):460次

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神經(jīng)突觸素1抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.

神經(jīng)突觸素1抗體

英文名稱 Synapsin 1
中文名稱 神經(jīng)突觸素1抗體
別    名 Brain protein 4.1; SYN 1; SYN 1a; SYN 1b; SYN I; SYN1; SYN1a; SYN1b; Synapsin 1; Synapsin1; SynapsinI; Synapsin-1; SYNI; SYN1_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  細胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 85kDa
細胞定位 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Synapsin I
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function:
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.

Subunit:
Homodimer. Interacts with CAPON. Forms a ternary complex with . Isoform Ib interacts with PRNP.
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