垂體腫瘤轉(zhuǎn)化基因抗體

英文名稱 Securin
中文名稱 垂體腫瘤轉(zhuǎn)化基因抗體
別    名 AW555095; C87862; Cut2; EAP 1; EAP1; ESP1 ASSOCIATED PROTEIN 1; Esp1-associated protein; hPTTG; MGC126883; MGC138276; Pds1; Pituitary tumor transforming 1; Pituitary tumor transforming protein 1; Pituitary tumor-transforming 1, isoform CRA_a; Pituitary tumor-transforming 1, isoform CRA_b; Pituitary tumor-transforming gene 1; Pituitary tumor-transforming gene 1 protein; PTTG 1; PTTG; PTTG1; PTTG1 protein; PTTG1_HUMAN; Pttg3; Securin; TUMOR TRANSFORMING 1; Tumor transforming protein 1; TUMOR-TRANSFORMING 1; Tumor-transforming protein 1; TUTR 1; TUTR1.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22-28kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTTG1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The encoded protein is a homolog of yeast securing proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013].xy-6083R    PHAP1蛋白磷酸酶2A抑制劑1抗體
xy-6086R    Pinin橋粒相關(guān)蛋白DRS抗體
xy-0376R    PDSS2抑癌蛋白DLP1抗體
xy-6085R    PRKCDBP蛋白激酶C delta結(jié)合蛋白抗體
xy-2197R    duck hepatitis A virus polyprotein鴨甲型肝炎病毒聚蛋白抗體
xy-2639R    PGE2前列腺素E2抗體
xy-2444R    Pleiotrophin多效生長因子抗體
xy-5920R    PATZ1轉(zhuǎn)錄調(diào)節(jié)因子MAZR抗體
xy-6833R    PDCD6凋亡相關(guān)蛋白6抗體
xy-12142R    PATJPSD95相關(guān)緊密連接蛋白PATJ抗體
xy-12157R    PDGFAA + PDGFBB血小板源性生長因子AA+BB抗體
xy-6316R    PTGER1前列腺素EP1受體抗體
xy-1871R    P4HTM脯氨酸水解酶4抗體
xy-6769R    PHAPI2酸性核磷蛋白32家族B抗體
xy-7666R    PDCD2L程序性細(xì)胞死亡2樣抗體
xy-4507R    PRRSV M protein豬藍(lán)耳病病毒M蛋白抗體
xy-9352R    Proteasome 20S alpha 3蛋白酶體PSMα3抗體
xy-9346R    Proteasome 19S 10B蛋白酶體PRS10B抗體
xy-9347R    Proteasome 26S S3蛋白酶體PSMD3抗體
xy-9370R    Cerebral protein 4腦蛋白4抗體
xy-9353R    Proteasome 20S alpha 3(Ser250)磷酸化蛋白酶體PSMα3抗體
xy-10178R    PDSS2抑癌蛋白DLP1
xy-12117R    POFUT1蛋白O巖藻糖基轉(zhuǎn)移酶1抗體
xy-12134R    PNCK鈣/鈣調(diào)素依賴蛋白激酶1β/CaMKIβ抗體
xy-0101R    PKM2丙酮酸激酶-M2抗體
xy-11140R    PCDHB7原鈣粘蛋白β7抗體
xy-1927R    uPA Receptor尿激酶型纖溶酶原激活因子受體抗體
xy-1861R    PAX5配對(duì)盒基因5抗體
xy-1870R    PEG3PEG3蛋白抗體