前列腺跨膜上皮1抗原抗體

英文名稱 STEAP1
中文名稱 前列腺跨膜上皮1抗原抗體
別    名 Six transmbrane epithelial antigen of the prostate; MGC19484; PRSS 24; PRSS24; Six transmembrane epithelial antigen of the prostate; STEAP 1; STEAP1; STEA1_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  上皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human STEAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell cell junctions.
Prostate cancer is the most frequently diagnosed cancer and is the second leading cause of cancer-related deaths in American men. Although the early serum detection of prostate-specific antigen (PSA) plays important roles in early diagnosis, it may not distinguish prostate cancer from benign diseases. Recently, a novel protein, which contains 339 amino acids, named STEAP (six transmembrane epithelial antigen of the prostate), was identified in advanced prostate cancer. STEAP is unique among the currently known prostate cancer markers because of its putative secondary structure, from which one may predict that it functions as a potential channel protein. STEAP is strongly expressed in advanced prostate cancer and some extent expression in other cancers, such as colon and ovarian cancer cell lines.

Function:
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xy-3517M    PAK4小鼠抗p21激活激酶4抗體
xy-7534R    PGC1 beta過氧化物酶體增殖物激活受體γ輔激活子1β抗體
xy-7535R    PGC1 alpha + beta過氧化物酶體增殖物激活受體γ輔激活子1α+β抗體
xy-11788R    Prion protein PrP/CD230朊病毒蛋白CD230抗體
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xy-7094R    p53AIP1p53調(diào)節(jié)凋亡誘導(dǎo)蛋白1抗體
xy-7101R    PTRH2Bcl-2轉(zhuǎn)錄抑制因子1抗體
xy-7099R    PLSCR3磷脂爬行酶3抗體
xy-7634R    PARL骨骼肌細(xì)胞線粒體膜蛋白PARL抗體
xy-7100R    PNPT1多核苷酸磷酸化酶蛋白抗體
xy-6382R    PTK5胃腸道相關(guān)酪氨酸激酶抗體（蛋白酪氨酸激酶5）
xy-6392R    PCNPPEST含核蛋白抗體
xy-3020R    phospho-p53BP1 (Ser25 + Ser29)磷酸化p53結(jié)合蛋白1抗體
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xy-3744R    Phospho-Paxillin(Tyr31)磷酸化樁蛋白Paxillin抗體
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xy-3963R    PKA R2蛋白激酶A受體2α亞基抗體
xy-4022R    phospho-PKA R2 (Ser96)磷酸化蛋白激酶A受體2α亞基抗體
xy-3964R    PKA gamma蛋白激酶Aγ抗體
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