細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子Smad-2抗體

英文名稱 Smad2
中文名稱 細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子Smad-2抗體
別    名 Mothers against decapentaplegic homolog 2; SMAD 2; Mothers against DPP homolog 2; Smad2; hMAD 2; hSMAD2; JV18 1; JV18; JV181; MAD; MAD Related Protein 2; MADH2; MADR2; MGC22139; MGC34440; Mothers Against Decapentaplegic Homolog 2; mothers against DPP homolog 2; SMAD 2; SMAD; SMAD2; SMAD2_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  生長(zhǎng)因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Smad2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SMAD2 or Mothers against decapentaplegic homolog 2 is a polypeptide that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decepentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF-Beta superfamily of modulators. Like many other TGF-Beta family members SMAD2 is involved in cell signalling. SMAD2 modulates signals of activin and TGF-Beta's. It interacts with SMAD anchor for receptor activation (SARA). The binding of ligands causes the phosphorylation of the SMAD2 protein and the dissociation from SARA and the association with SMAD4. It is subsequently transferred to the nucleus where it forms complexes with other proteins and acts as a transcription factor. SMAD2 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase. This antibody is cross reactive with Smad3.xy-11613R    TAS2R9味覺受體蛋白家族2亞基9抗體
xy-2726R    TPSB2肥大細(xì)胞類胰蛋白酶β2
xy-5525R    phospho-TrkB (Tyr515)磷酸化酪氨酸激酶B抗體
xy-6026R    TSLC1細(xì)胞粘附分子1抗體
xy-3794R    TMEM16A跨膜蛋白16A/鈣激活氯離子通道抗體
xy-2150R    TNF-alpha腫瘤壞死因子-α抗體
xy-7091R    TP53I11腫瘤蛋白P53誘導(dǎo)蛋白11抗體
xy-11789R    TAS2R49味覺2型受體蛋白家族49抗體
xy-9577R    TSPEAR早期未分化視網(wǎng)膜及晶狀體蛋白EURL抗體
xy-11413R    TSKS睪丸特異激酶底物蛋白抗體
xy-4285R    TPX2微管相關(guān)同源蛋白TPX2抗體
xy-7538R    TRIB3神經(jīng)細(xì)胞死亡誘導(dǎo)蛋白激酶抗體
xy-4511R    tubulin Beta微管蛋白β tubulin抗體 Tubulin β
xy-5736R    TACC2轉(zhuǎn)化酸性卷曲含蛋白質(zhì)2
xy-2676M    TSHB小鼠抗促甲狀腺素抗體
xy-6263R    TTBK1腦源性tau蛋白激酶抗體
xy-11772R    Tetanus Toxin heavy chain破傷風(fēng)毒素重鏈抗體
xy-6284R    TKTL1酮基移換酶樣蛋白1抗體
xy-6286R    TMPRSS4膜型絲氨酸蛋白酶2抗體
xy-6113R    TCHP抑癌蛋白TCHP抗體
xy-9428R    Tal1T細(xì)胞急性淋巴細(xì)胞性白血病1蛋白/淋巴瘤蛋白5抗體
xy-9429R    TXNDC9胚胎干細(xì)胞相關(guān)蛋白TXNDC9抗體
xy-9812R    TCF9轉(zhuǎn)錄因子9抗體
xy-1663R    THOC2轉(zhuǎn)錄因子THOC2抗體
xy-9870R    Thymosin beta 4胸腺素β4抗體
xy-4907R    TGF beta 3轉(zhuǎn)移生長(zhǎng)因子β3（TGFβ3）抗體
xy-4908R    TGF beta 1轉(zhuǎn)化生長(zhǎng)因子β（TGFβ）抗體
xy-4909R    TGF beta 2轉(zhuǎn)化生長(zhǎng)因子β2（TGFβ2）抗體
xy-7579R    TXNDC5硫氧還蛋白5抗體
xy-9861R    CMD1G擴(kuò)張型心肌病蛋白1G抗體