鋅指蛋白141抗體

英文名稱 ZNF141
中文名稱 鋅指蛋白141抗體
別    名 D4S90; PAPA6; pHZ-44; Zinc finger protein 141.

說 明 書 0.2ml  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF141
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders.

Function:
May be involved in transcriptional regulation as a repressor. Plays a role in limb development.

Subcellular Location:
Nuclear.

DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.
Disease description:A condition characterized by the occurrence of supernumerary digits in the upper and/or lower extremities. In postaxial polydactyly type A, the extra digit is well-formed and articulates with the fifth or a sixth metacarpal/metatarsal.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 11 C2H2-type zinc fingers. Contains 1 KRAB domain.

Database links:

Entrez Gene: 7700 Human

Omim: 194648 Humanxy-6293R    Prostatic Acid Phosphatase前列腺酸性磷酸酶抗體
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xy-5826R    PCDHAC1原鈣粘蛋白1抗體
xy-5814R    Prominin 2造血干細(xì)胞抗原CD133相關(guān)蛋白抗體
xy-6266R    PTK6酪氨酸蛋白激酶6/乳腺腫瘤激酶抗體
xy-5734R    PCGF1表觀抑制因子Polycomb家族成員PCGFl蛋白抗體
xy-11133R    PCDHAC2原鈣粘蛋白介導(dǎo)的PCDHαC2受體抗體
xy-3517M    PAK4小鼠抗p21激活激酶4抗體
xy-7534R    PGC1 beta過氧化物酶體增殖物激活受體γ輔激活子1β抗體
xy-7535R    PGC1 alpha + beta過氧化物酶體增殖物激活受體γ輔激活子1α+β抗體
xy-11788R    Prion protein PrP/CD230朊病毒蛋白CD230抗體
xy-11410R    Progestin Receptor Beta孕激素受體β（MPRβ）抗體
xy-11411R    PTGFR前列腺素F2a受體抗體PGF2αR
xy-6350R    pan methyl Lysine泛甲基賴氨酸抗體
xy-6370R    p70 S6 kinase alpha核糖體p70 S6蛋白激酶抗體
xy-7094R    p53AIP1p53調(diào)節(jié)凋亡誘導(dǎo)蛋白1抗體
xy-7101R    PTRH2Bcl-2轉(zhuǎn)錄抑制因子1抗體
xy-7099R    PLSCR3磷脂爬行酶3抗體
xy-7634R    PARL骨骼肌細(xì)胞線粒體膜蛋白PARL抗體
xy-7100R    PNPT1多核苷酸磷酸化酶蛋白抗體
xy-6382R    PTK5胃腸道相關(guān)酪氨酸激酶抗體（蛋白酪氨酸激酶5）
xy-6392R    PCNPPEST含核蛋白抗體
xy-3020R    phospho-p53BP1 (Ser25 + Ser29)磷酸化p53結(jié)合蛋白1抗體
xy-3756R    PP1A蛋白磷酸酶2Cα抗體
xy-3744R    Phospho-Paxillin(Tyr31)磷酸化樁蛋白Paxillin抗體
xy-3806R    PGP9.5神經(jīng)細(xì)胞胞漿蛋白9.5抗體（蛋白基因產(chǎn)物9.5）
xy-4024R    phospho-PKA beta(Ser338)磷酸化蛋白激酶Aβ抗體
xy-3963R    PKA R2蛋白激酶A受體2α亞基抗體
xy-4022R    phospho-PKA R2 (Ser96)磷酸化蛋白激酶A受體2α亞基抗體
xy-3964R    PKA gamma蛋白激酶Aγ抗體
xy-3965R    PKA regulatory subunit I beta蛋白激酶受體相關(guān)1β抗體
xy-6466R    PRDM1B淋巴細(xì)胞誘導(dǎo)成熟蛋白1抗體
xy-5179R    phospho-PTPRA(Tyr798)磷酸化酪氨酸磷酸酶α抗體
xy-3969R    PRKAR1蛋白激酶A調(diào)節(jié)亞基a1抗體
xy-5175R    phospho-PTPRA (Ser180)磷酸化酪氨酸磷酸酶α抗體