ZCCHV蛋白抗體

英文名稱 ZCCHV
中文名稱 ZCCHV蛋白抗體
別    名 ADP ribosyltransferase diphtheria toxin like 13; ARTD13; FLB6421; PARP13; ZAP; ZC3H2; ZC3HAV 1; Zc3hav1; ZC3HDC 2; ZC3HDC2; ZCCHV_HUMAN; Zinc finger antiviral protein; Zinc finger CCCH domain containing protein 2; Zinc finger CCCH domain-containing antiviral protein 1; Zinc finger CCCH domain-containing protein 2; Zinc finger CCCH type antiviral 1; Zinc finger CCCH type antiviral protein 1; Zinc finger CCCH-type antiviral protein 1.
   
說 明 書 0.2ml  
研究領(lǐng)域 免疫學  細菌及病毒  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZCCHV
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described. [provided by RefSeq, Jul 2008]

Function:
Antiviral protein which inhibits the replication of viruses by recruiting the cellular RNA degradation machineries to degrade the viral mRNAs. Binds to a ZAP-responsive element (ZRE) present in the target viral mRNA, recruits cellular poly(A)-specific ribonuclease PARN to remove the poly(A) tail, and the 3'-5' exoribonuclease complex exosome to degrade the RNA body from the 3'-end. It also recruits the decapping complex DCP1-DCP2 through RNA helicase p72 (DDX17) to remove the cap structure of the viral mRNA to initiate its degradation from the 5'-end. Its target viruses belong to families which include retroviridae: human immunodeficiency virus type 1 (HIV-1), moloney and murine leukemia virus (MoMLV) anxy-0370R-AF488    Rabbit Anti-Goat IgM/Alexa Fluor 488Alexa Fluor 488標記的兔抗羊IgM
xy-0370R-xyy3    Rabbit Anti-Goat IgM/Cy3Cy3標記的兔抗羊IgM
xy-0370R-xyy5    Rabbit Anti-Goat IgM/Cy5Cy5標記的兔抗羊IgM
xy-0370R-xyy5.5    Rabbit Anti-Goat IgM/Cy5.5Cy5.5標記的兔抗羊IgM
xy-0370R-xyy7    Rabbit Anti-Goat IgM/Cy7Cy7標記的兔抗羊IgM
xy-0370R-xyE    Rabbit Anti-Goat IgM/PEPE標記的兔抗羊IgM
xy-0370R-Bio    Rabbit Anti-Goat IgM/Bio生物素標記的兔抗羊IgM
xy-0370R-HRxy    Rabbit Anti-Goat IgM/HRP辣根過氧化物酶標記的兔抗羊IgM
xy-0358R-HRxy    Rabbit Anti-Guinea pig IgG/HRP辣根過氧化物酶標記的兔抗豚鼠IgG
xy-0358R-Golxy    Rabbit Anti-Guinea pig IgG/Gold膠體金標記的兔抗豚鼠IgG
xy-0358R-Bio    Rabbit Anti-Guinea pig IgG/Bio生物素標記的兔抗豚鼠IgG
xy-0358R-xyy3    Rabbit Anti-Guinea pig IgG/Cy3Cy3標記的兔抗豚鼠IgG
xy-0358R-xyy5    Rabbit Anti-Guinea pig IgG/Cy5Cy5標記的兔抗豚鼠IgG
xy-0358R-xyy5.5    Rabbit Anti-Guinea pig IgG/Cy5.5Cy5.5標記的兔抗豚鼠IgG
xy-0358R-xyy7    Rabbit Anti-Guinea pig IgG/Cy7Cy7標記的兔抗豚鼠IgG
xy-0358R-xyE    Rabbit Anti-Guinea pig IgG/PEPE標記的兔抗豚鼠IgG
xy-0358R-xyE-xyy3    Rabbit Anti-Guinea pig IgG/PE-Cy3PE-Cy3標記的兔抗豚鼠IgG
xy-0358R-xyE-xyY5    Rabbit Anti-Guinea pig IgG/PE-CY5PE-CY5標記的兔抗豚鼠IgG
xy-0358R-Axyxy    Rabbit Anti-Guinea pig IgG/APCAPC標記的兔抗豚鼠IgG
xy-0358R-AF350    Rabbit Anti-Guinea pig IgG/Alexa Fluor 350Alexa Fluor 350標記的兔抗豚鼠IgG
xy-0358R-AF488    Rabbit Anti-Guinea pig IgG/Alexa Fluor 488Alexa Fluor 488標記的兔抗豚鼠IgG
xy-0358R-Axy    Rabbit Anti-Guinea pig IgG/AP堿性磷酸酶（AP）標記的兔抗豚鼠IgG
xy-0358R-FITxy    Rabbit Anti-Guinea pig IgG/FITCFITC標記的兔抗豚鼠IgG
xy-0358R-AF555    Rabbit Anti-Guinea pig IgG/Alexa Fluor 555Alexa Fluor 555標記的兔抗豚鼠IgG
xy-0358R-AF647    Rabbit Anti-Guinea pig IgG/Alexa Fluor 647Alexa Fluor 647標記的兔抗豚鼠IgG
xy-0358R-xyE-xyy5.5    Rabbit Anti-Guinea pig IgG/PE-Cy5.5PE-Cy5.5標記的兔抗豚鼠IgG
xy-0358R-xyE-xyy7    Rabbit Anti-Guinea pig IgG/PE-Cy7PE-Cy7標記的兔抗豚鼠IgG
xy-0358R-RBITxy    Rabbit Anti-Guinea pig IgG/RBITC羅丹明標記的兔抗豚鼠IgG
xy-0375R-xyy5.5    Rabbit Anti-Guinea pig IgM/Cy5.5Cy5.5標記的兔抗豚鼠IgM
xy-0375R-xyy7    Rabbit Anti-Guinea pig IgM/Cy7Cy7標記的兔抗豚鼠IgM
xy-0375R-xyE    Rabbit Anti-Guinea pig IgM/PEPE標記的兔抗豚鼠IgM
xy-0375R-RBITxy    Rabbit Anti-Guinea pig IgM/RBITC羅丹明標記的兔抗豚鼠IgM