在生物醫(yī)學(xué)研究和臨床診斷中，免疫球蛋白M（IgM）是評(píng)估小鼠免疫狀態(tài)的重要生物標(biāo)志物。IgM是B細(xì)胞初次應(yīng)答中產(chǎn)生的第一個(gè)抗體類別，對(duì)于識(shí)別和測量IgM水平，IgM (小鼠) ELISA試劑盒提供了一種高效、靈敏的解決方案。

艾美捷IgM (小鼠) ELISA Kit：

貨號(hào)：BGT-KET-109

抗體類型：ELISA

反應(yīng)性：小鼠/鼠類

宿主：山羊

特異性/目標(biāo)：IgM

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檢測范圍：25 ng/ml - 800 ng/ml

靈敏度：2.786 ng/ml

檢測時(shí)間：100分鐘

樣本類型：血漿，血清

儲(chǔ)存：2-8°C

IgM (小鼠) ELISA Kit檢測原理：

組成和優(yōu)勢(shì)：

預(yù)包被的96孔板條，用于固定抗體

檢測抗體，通常標(biāo)記有酶，如辣根過氧化物酶（HRP）

酶底物，用于產(chǎn)生可測量的信號(hào)

標(biāo)準(zhǔn)品和校準(zhǔn)曲線生成所需的試劑

詳細(xì)的操作手冊(cè)和數(shù)據(jù)分析指南

優(yōu)勢(shì)：

高靈敏度和特異性，確保結(jié)果的準(zhǔn)確性

操作簡便，適合高通量實(shí)驗(yàn)

試劑穩(wěn)定性好，便于長期存儲(chǔ)和使用

IgM (小鼠) ELISA Kit部分文獻(xiàn)參考：

Publications citing ICL's Mouse IgM ELISA Kit:

Zhang S, Dubois W, Feng X, Nguyen JT, Young NS, Mock BA. Conditional deletion of mTOR discloses its essential role in early B-cell development. Mol Carcinog. 2022;61(4):408-416. doi:10.1002/mc.23386

Jessica M. Mayeux et al. Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse Front. Immunol., 26 April 2018 

Mayeux JM, Escalante GM, Christy JM, Pawar RD, Kono DH, Pollard KM. Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse. Front Immunol. 2018;9:874. Published 2018 Apr 26. doi:10.3389/fimmu.2018.00874

Sharma NS, Lal CV, Li JD, et al. The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol. 2018;315(5):L653-L661. doi:10.1152/ajplung.00308.2017

Franz B et al. Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB Journal of Immunology Research Volume 2015 (2015), Article ID 840842, 13 pages

Zhang S, Pruitt M, Tran D, et al. B cell-specific deficiencies in mTOR limit humoral immune responses. J Immunol. 2013;191(4):1692-1703. doi:10.4049/jimmunol.1201767

Capoccia B et al. Transcription factor MIST1 in terminal differentiation of mouse and human plasma cells Physiological Genomics Published 1 February 2011 Vol. 43 no. 3, 174-186 DOI: 10.1152/physiolgenomics.00084.2010

Santiago M et al. Innate Retroviral Restriction by Apobec3 Promotes Antibody Affinity Maturation In Vivo The Journal of Immunology July 15, 2010 vol. 185 no. 2 1114-1123

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anti-Mouse IgM Antibody (Goat) - Affinity Purified