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Source

Rabbit

Applications

WB

Reactivity

Human, Mouse,Rat

Dilution

WB 1:500-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of AL4A1 at Human/Mouse/Rat

Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen

Synthesized peptide derived from human AL4A1

Uniprot No

P30038

Alternative names

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.5.1.12) (Aldehyde dehydrogenase family 4 member A1)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.103% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2009],

Other

ALDH4A1 ALDH4 P5CDH, AL4A1

Concentration

1 mg/ml