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ISO-1

CAS No. : 478336-92-4

MCE 國際站：ISO-1

產(chǎn)品活性：ISO-1 是巨噬細胞移動抑制因子(MIF) 拮抗劑，IC₅₀ 值為 7 μM。

研究領域：Immunology/Inflammation

作用靶點：Macrophage migration inhibitory factor (MIF)

In Vitro: ISO-1 (0.1-20 μM; 16 hours) has a slight inhibitory effect on Cox-2 secretion without the addition of recombinant MIF.

In Vivo: ISO-1 (injected intraperitoneally; 3.5-35 mg/kg; twice daily; 2 weeks) improves the survival rate from lethal endotoxemia and shows the anti-inflammatory effect.
ISO-1 (intraperitoneal injection; 35 mg/kg; twice daily; 3 days) causes a significant reduction in average implant size and decreases Flk1 expression in implants.

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