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Spring Bioscience代理，spring bioscience絲氨酸/蘇氨酸蛋白激酶B-RAF（BRAF）是Raf家族的一員。 BRAF突變?cè)诹夹院蛺盒阅[瘤是常見(jiàn)的。 BRAF改變和突變誘導(dǎo)激活段的構(gòu)象變化中BRAF V600E突變占絕大多數(shù)，導(dǎo)致組成型激酶活性的BRAF的和下游目標(biāo)連續(xù)的磷酸化。已在黑色素瘤，甲狀腺乳頭狀癌，多形性xanthoastrocytomas，朗格漢斯細(xì)胞組織細(xì)胞增生癥，卵巢交界性腫瘤，節(jié)細(xì)胞膠質(zhì)瘤，結(jié)直腸癌，毛細(xì)胞型星形細(xì)胞瘤檢測(cè)到BRAF V600E突變。
Spring Bio,Spring Bio代理,Spring Bioscience
| PRODUCT DETAILS: | |||
| TechnologyMouse Monoclonal | |||
| Clone NameVE1 | |||
| ApplicationIHC-P, WB | |||
| Species Reactivity | |||
| TestedHu | |||
| Predicted by homology | |||
| IsotypeMouse IgG2a | |||
| ImmunogenSynthetic peptide representing the BRAF V600E mutated amino acid sequence from amino acid 596 to 606 （GLATEKSRWSG） | |||
| Cellular LocalizationCytoplasm | |||
| Control TissueColon Carcinoma with BRAF V600E mutation | |||
| Regulatory RatingResearch Use Only （RUO） | |||
| Entrez673 | |||
| Storage Requirement2-8°C | |||
| Target Molecular Weight95 kDa | |||
| FormulationRefer to Data Sheet | |||
| Catalog No. | Volume | Dilution | |
| E19290 | 0.1ml | 50 | |
| E19292 | 0.5ml | 50 | |
| E19294 | 1.0ml | 50 | |
